鏅虹爺鍜ㄨ - 浜т笟淇℃伅闂ㄦ埛

鎴戝浗绉戝瀹跺彂鐜癱ircRNA鑳藉淇冭繘琛€绠′慨澶�

鐜姸RNA锛坈ircRNA锛夊湪澶ц剳涓惈閲忎赴瀵岋紝澶氱circRNA鍦ㄥ姛鑳戒笂涓庣己琛€鎬ц剳鍗掍腑鏈夊叧銆傝绠′慨澶嶈璁や负鏄敼鍠勭己琛€鎬ц剳鍗掍腑鍚庨暱鏈熼鍚庣殑鍏抽敭鎭㈠鎺柦銆侼6-鐢插熀鑵哄槍鍛わ紙m6A锛夋槸鐪熸牳鐢熺墿淇′娇RNA锛坢RNA锛変笂鏈€鏅亶鐨勫唴閮ㄤ慨楗帮紝浠嬪琛€绠′慨澶嶃€傜劧鑰岋紝circRNA SCMH1锛坈ircSCMH1锛変績杩涜绠′慨澶嶇殑鍒嗗瓙鏈哄埗灏氫笉鏄庣‘銆傝繎鏈燂紝涓滃崡澶у鍜屼腑鍥界瀛﹂櫌鏄嗘槑鍔ㄧ墿鐮旂┒鎵€鐨勭爺绌朵汉鍛樺彂鐜帮紝CircSCMH1閫氳繃鑴傝偑鍜岃偉鑳栫浉鍏宠泲鐧斤紙FTO锛夎皟鎺х殑m6A淇グ澧炲己琛€绠′慨澶嶃€傜爺绌舵垚鏋滃彂琛ㄥ湪銆奛ature Communications銆嬫湡鍒婏紝鏍囬涓衡€淔TO-dependent m6A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke鈥濄€�


鐮旂┒浜哄憳棣栧厛閫氳繃鍏夊寲瀛︽硶寤虹珛灏忛紶涓庢亽娌崇尨缂鸿鎬ц剳鍗掍腑妯″瀷锛岀劧鍚庡垎鍒敞灏勯澏鍚戝ぇ鑴戝苟鍖呰9circSCMH1鐨勭粏鑳炲鍥婃场锛圗V-circSCMH1锛夛紝鐮旂┒缁撴灉琛ㄦ槑锛孍V-circSCMH1鑳藉鏈夋晥淇冭繘缂鸿鎬ц剳鍗掍腑妯″瀷鐨勮绠′慨澶嶏紝骞朵笖鏄捐憲闄嶄綆鍗掍腑妯″瀷灏忛紶鑴戦儴缂鸿璇卞鐨刴6A淇グ锛屼絾涓嶅奖鍝嶅崚涓悗鐨凢TO姘村钩銆傝繘涓€姝ョ爺绌惰〃鏄庯紝CircSCMH1閫氳繃娉涚礌鍖栧鍔犺剳琛€绠″唴鐨粏鑳濬TO浠庣粏鑳炶川鍒扮粏鑳炴牳鐨勬槗浣嶏紝瀵艰嚧琛€绠$敓鎴愮浉鍏冲熀鍥燩lpp3 mRNA鐨刴6A淇グ闄嶄綆锛屼粠鑰屾姂鍒朵簡鍐呯毊缁嗚優涓璓lpp3鐨勯檷瑙o紝浣縋lpp3缂栫爜鐨凩PP3铔嬬櫧姘村钩澧炲姞锛屼績杩涜绠′慨澶嶃€�


鎬讳箣锛岃繖椤圭爺绌朵负circSCMH1淇冭繘鍗掍腑鍚庤绠′慨澶嶇殑鏈哄埗鎻愪緵浜嗘柊瑙佽В锛屽苟涓烘不鐤楃己琛€鎬ц剳鍗掍腑鐨勬柊鑽爺鍙戞彁渚涗簡鏂版€濊矾鍜屾柊闈剁偣銆�


娉細姝ょ爺绌舵垚鏋滄憳鑷€奛ature Communications銆嬫湡鍒婂師鏂囩珷锛屾枃绔犲唴瀹逛笉浠h〃鏈綉绔欒鐐瑰拰绔嬪満锛屼粎渚涘弬鑰冦€�


鐭ュ墠娌匡紝闂櫤鐮斻€傛櫤鐮斿挩璇㈡槸涓浗涓€娴佷骇涓氬挩璇㈡満鏋勶紝鍗佹暟骞存寔缁繁鑰曚骇涓氱爺绌堕鍩燂紝鎻愪緵娣卞害浜т笟鐮旂┒鎶ュ憡銆佸晢涓氳鍒掍功銆佸彲琛屾€х爺绌舵姤鍛婂強瀹氬埗鏈嶅姟绛変竴绔欏紡浜т笟鍜ㄨ鏈嶅姟銆備笓涓氱殑瑙掑害銆佸搧璐ㄥ寲鐨勬湇鍔°€佹晱閿愮殑甯傚満娲炲療鍔涳紝涓撴敞浜庢彁渚涘畬鍠勭殑浜т笟瑙e喅鏂规锛屼负鎮ㄧ殑鎶曡祫鍐崇瓥璧嬭兘銆�


10000 11604
绮惧搧鎶ュ憡鏅虹爺鍜ㄨ - 绮惧搧鎶ュ憡
2024-2030骞翠腑鍥藉尰鐤桹2O琛屼笟甯傚満绔炰簤鐜扮姸鍙婂彂灞曞墠鏅爺鍒ゆ姤鍛�
2024-2030骞翠腑鍥藉尰鐤桹2O琛屼笟甯傚満绔炰簤鐜扮姸鍙婂彂灞曞墠鏅爺鍒ゆ姤鍛�

銆�2024-2030骞翠腑鍥藉尰鐤桹2O琛屼笟甯傚満绔炰簤鐜扮姸鍙婂彂灞曞墠鏅爺鍒ゆ姤鍛娿€嬪叡鍗佺珷锛屽寘鍚腑鍥藉尰鐤桹2O琛屼笟閲嶇偣浼佷笟甯冨眬妗堜緥鐮旂┒锛屼腑鍥藉尰鐤桹2O甯傚満鍓嶆櫙棰勬祴鍙婂彂灞曡秼鍔块鍒わ紝涓浗鍖荤枟O2O鎶曡祫鎴樼暐瑙勫垝绛栫暐鍙婂缓璁瓑鍐呭銆�

濡傛偍鏈夊叾浠栬姹傦紝璇疯仈绯伙細

鐗堟潈鎻愮ず锛氭櫤鐮斿挩璇㈠€″灏婇噸涓庝繚鎶ょ煡璇嗕骇鏉冿紝瀵规湁鏄庣‘鏉ユ簮鐨勫唴瀹规敞鏄庡嚭澶勩€傚鍙戠幇鏈珯鏂囩珷瀛樺湪鐗堟潈銆佺ǹ閰垨鍏跺畠闂锛岀儲璇疯仈绯绘垜浠紝鎴戜滑灏嗗強鏃朵笌鎮ㄦ矡閫氬鐞嗐€傝仈绯绘柟寮忥細gaojian@chyxx.com銆�010-60343812銆�

鍦ㄧ嚎鍜ㄨ
寰俊瀹㈡湇
寰俊鎵爜鍜ㄨ瀹㈡湇
鐢佃瘽瀹㈡湇

鍜ㄨ鐑嚎

400-700-9383
010-60343812
杩斿洖椤堕儴
鍦ㄧ嚎鍜ㄨ
鐮旂┒鎶ュ憡
鍟嗕笟璁″垝涔�
椤圭洰鍙爺
瀹氬埗鏈嶅姟
杩斿洖椤堕儴