绉戝瀹惰繘琛屾渶澶ц妯＄殑榛戣壊绱犵槫鍏ㄥ熀鍥犵粍娴嬪簭鐮旂┒

榛戠礌鐦ゆ槸涓€绉嶉粦绱犵粏鑳炵檶锛屾牴鎹韩浣撻儴浣嶇殑浣嶇疆鏈夊绉嶄簹鍨嬶紝灏界宸叉湁鏂囩尞閽堝榛戣壊绱犵槫鐨勫熀鍥犵粍鏅杩涜鍒嗘瀽锛屼絾鏄粛缂轰箯鏇村叏闈㈢殑鍩哄洜缁勭爺绌躲€�

鍙戣〃鍦ㄣ€奀ancer Discovery銆嬩笂鐨勪竴椤归涓衡€淐omparative genomics provides etiological and biological insights into melanoma subtypes鈥濈殑鐮旂┒涓紝浜氭槅澹叞鍖诲鐮旂┒鎵€涓庢倝灏煎ぇ瀛︾爺绌朵汉鍛樺叡鍚岃繘琛屼簡杩勪粖鏈€澶ц妯＄殑榛戣壊绱犵槫鍏ㄥ熀鍥犵粍鍒嗘瀽銆�

鐮旂┒浜哄憳瀵�570渚嬫偅鑰呯殑鍏ㄥ熀鍥犵粍鏁版嵁锛� 230涓偪鐦ょ殑杞綍缁勬祴搴忔暟鎹紝鐢插熀鍖栬姱鐗�144涓偪鐦ゆ暟鎹繘琛屽垎鏋愶紝鍦ㄥ洓绫讳簹鍨嬩腑锛岀毊鑲ら粦鑹茬礌鐦ょ殑鑲跨槫绐佸彉璐熻嵎鏈€楂橈紝鑰岃偄绔粦鑹茬礌鐦ゅ拰绮樿啘榛戣壊绱犵槫鐨勫垯灞呬腑锛岃憽钀勮啘榛戣壊绱犵槫涓烘渶浣庛€傜爺绌朵汉鍛樿繘涓€姝ュ垎鏋愪簡鍥涚被浜氬瀷鐨勫樊寮傛€т笌鐩镐技鎬э紝骞惰瘑鍒簡娼滃湪鐨勬柊榛戣壊绱犵槫涓€浜涗笉澶父瑙佺殑榛戣壊绱犵槫浜氬瀷鐨勬槗鎰熷熀鍥犮€�

璇ョ爺绌惰繘琛屼簡杩勪粖涓烘鏈€澶ц妯＄殑榛戣壊绱犵槫鍏ㄥ熀鍥犵粍鐮旂┒锛屼负娣卞叆浜嗚В褰卞搷榛戣壊绱犵槫鐨勭梾鍥犮€佺敓鐗╁鍜屾偅鑰呯殑娌荤枟鎻愪緵渚濇嵁銆�

璁烘枃閾炬帴锛�

https://aacrjournals.org/cancerdiscovery/article/doi/10.1158/2159-8290.CD-22-0603/709186/Comparative-genomics-provides-etiological-and?searchresult=1

娉細姝ょ爺绌舵垚鏋滄憳鑷€奀ancer Discovery銆嬶紝鏂囩珷鍐呭涓嶄唬琛ㄦ湰缃戠珯瑙傜偣鍜岀珛鍦猴紝浠呬緵鍙傝€冦€�

鐭ュ墠娌匡紝闂櫤鐮斻€傛櫤鐮斿挩璇㈡槸涓浗涓€娴佷骇涓氬挩璇㈡満鏋勶紝鍗佹暟骞存寔缁繁鑰曚骇涓氱爺绌堕鍩燂紝鎻愪緵娣卞害浜т笟鐮旂┒鎶ュ憡銆佸晢涓氳鍒掍功銆佸彲琛屾€х爺绌舵姤鍛婂強瀹氬埗鏈嶅姟绛変竴绔欏紡浜т笟鍜ㄨ鏈嶅姟銆備笓涓氱殑瑙掑害銆佸搧璐ㄥ寲鐨勬湇鍔°€佹晱閿愮殑甯傚満娲炲療鍔涳紝涓撴敞浜庢彁渚涘畬鍠勭殑浜т笟瑙ｅ喅鏂规锛屼负鎮ㄧ殑鎶曡祫鍐崇瓥璧嬭兘銆�